Ligand Design for LYTAC Extracellular Protein Degradation
Time: 3:30 pm
day: Conference Day One
Details:
- Learn how Lysosomal Targeting Chimeras (LYTACs) offer a new opportunity to target classes of secreted proteins which have been challenging for existing therapeutic inhibitors
- Unveil small molecule linker-ligands designed for optimal receptor binding, bioconjugation, and stability of conjugates has enabled new applications using small molecule-protein based LYTACs
- Design and properties of LYTACs to maximize efficiency of target protein degradation
