Pre-Conference Workshop Day: May 6, 2025

9:00 am – 12:00 pm Workshop A

Analyzing Payload Properties & Landscape to Enable Systematic Selection Strategies

  • Zhaohui Sunny Zhou Professor, Department of Chemistry & Chemical Biology, Northeastern University
  • Corey Reeves Senior Director & Head of Medicinal Chemistry, Hexagon Bio

Synopsis

Understanding the technical differences and potentials of payload-linker combinations is key to inform selection strategies. Join this collaborative space to analyze payload modes of action, benchmark emerging data, and gain a deeper understanding of payload diversity.

This workshop will gather experts to discuss:

  • A quantitative evaluation of payload-linker combination efficacy
  • Analysis of novel payload PK/PD profiles to guide design decisions
  • A review of physicochemical properties, including hydrophobicity, stability, and release kinetics
  • Debate about therapeutic areas and potential indications

12:00pm Lunch & Networking Break

1:00 pm – 4:00 pm Workshop B

Conducting Strategic Analysis to Differentiate ADC Programs in a Competitive Landscape

  • Robert Lutz Chief Scientific Officer, Iksuda Therapeutics

Synopsis

Navigate the competitive landscape of ADC development by exploring strategic approaches to differentiate your payload programs. This is your platform to gain actionable insights from industry leaders to help you identify niche opportunities, overcome challenges, and future-proof your portfolio in a crowded market.

This workshop will gather experts to discuss:

  • Performing SWOT analyses for payload categories and novel payload innovation vs. off-patent payload optimization
  • Lessons learned from clinical failures to distinguish payload-specific issues from broader ADC platform challenges
  • Identifying and leveraging emerging market opportunities to maximize payload value
Conference Day One
Event Guide