Structural Insights Into Next-Generation ISACs for Tumor-Specific Immune Activation
Time: 9:15 am
day: Conference Day One
Details:
- Discussing data demonstrating ISAC induced localized activation of innate immunity within the tumor microenvironment while minimizing systemic immune effects
- Preclinical validation of multiple tumor targets, including data from lead candidate BDC4182 in gastric and pancreatic cancers
- Overcoming challenges in TLR 7/8 Agonist payload conjugation chemistry
