Discuss & Understand the Diversity of the Contemporary Payload Toolbox to Benchmark Your Warheads, Make Informed Payload-Selection Choices & Optimize Your Chemistry for Clinical Success
Thank you to our speakers, sponsors, and delegates who joined us in Boston for the summit! If you are interested in the 2026 event, please get in touch at adc@hansonwade.com
As the ADC landscape became more competitive, the limited availability of targets and antigens highlighted the need to diversify payload modes of action to address cancers with high unmet needs.
As part of the World ADC Series, the 2nd ADC Payload Summit returned to Boston to help you turbocharge your ADCs by platforming cutting-edge work into diverse and novel payload categories
With new data on underutilized MOAs such as degraders, RNA polymerase II inhibitors, immunomodulators, gene silences, and splice modulators, this was a prime opportunity to meet with fellow peers to explore the merits and challenges of diverse payloads to help you drive the potency of your next first-in-class ADC
At this summit, our delegates gained critical insights to:
It’s exciting to see and learn about new and emerging ADC payloads!
Despite a long history of ADCs, the payloads at the clinical stage are mostly limited to a small number of cytotoxic molecules. Recently we have seen rapid expansion of payload classes used in preclinical ADC research. Research groups sharing experiences and learnings from each program will greatly benefit the field as we continue to explore various payload mechanism of action
This was a highly specialized meeting which focused on the latest developments of payloads targeting immunology-oncology space.
CHARACTERIZE
the physiochemical properties of novel payloads
INNOVATE and OPTIMIZE
the medicinal chemistry of traditional payloads by comparing underutilized mechanisms
BENCHMARK
payload selection strategies tailored to indications
ENHANCE
structure-activity relationships by modifying payload-linker designs
View The 2025 Full Event Guide:
- 3 Deep-dive days addressing the contemporary payload landscape through both a scientific and strategic lens
- Unrivalled insights from biopharma leaders including Heidelberg, Eisai, Merck, and more
- A full ADC payload landscape breakdown of 800+ candidates by stage and mechanism
...and more!
2025 World-Class Speaker Faculty Included:
2025 Official Partners:
Explore the Agenda
Discover the key scientific discussions from the ADC Payload Summit, covering advances in payload discovery, medicinal chemistry, and next-generation ADC mechanisms.
Partner With Us
Showcase your solutions alongside organizations advancing ADC payload chemistry, linker-payload design, and manufacturing innovation.
Join ADC & Biopharma Experts
Connect with ADC scientists, biopharma leaders, and innovators working to advance the next generation of targeted therapeutics.